Sometimes, more is not better, as researchers report in a new study of implantable defibrillators, devices that use electrical shocks to prevent sudden cardiac arrest in people with potentially life-threatening heart arrhythmias. In research published today in JAMA, investigators found… Read More ›
Comparative Effectiveness
Author Insights: Many Devices Approved Without Comparative Effectiveness Data
About half of high-risk cardiac devices approved by the US Food and Drug Administration (FDA) were approved without comparative data on whether they provide better outcomes than other treatment options, found an analysis published online in JAMA. Advances in medical… Read More ›
JAMA Forum: Bill Would Gut Patient-Centered Outcomes Research
Last week, the House Appropriations subcommittee on labor, health and human services, and education approved a spending bill, which moves along this week to the full committee for consideration and possible amendments. Then, it’s on to a vote in the… Read More ›
Author Insights: Refocus Questionable US-Funded Complementary and Alternative Therapies Research
The mission of the National Institutes of Health’s (NIH) National Center for Complementary and Alternative Medicine (NCCAM) is “to define, through rigorous scientific investigation, the usefulness and safety of complementary and alternative medicine interventions and their roles in improving health… Read More ›
Author Insights: Newer Radiation Therapy for Prostate Cancer More Expensive But Not Necessarily More Effective
An emerging type of radiation therapy for treating localized prostate cancer called proton therapy appears to be no better in reducing the risk of disease recurrence than the current standard of radiotherapy care, intensity-modulated radiation therapy (IMRT), but it is… Read More ›
For Many Women, Pelvic Floor Muscle Exercises Trump Drugs in Reducing Bladder Leaks
When women’s perspectives on treatment success are considered, pelvic floor muscle exercises are effective at reducing urinary incontinence in women with fewer adverse effects than drug-based treatment, according to a review by the Agency for Healthcare Research and Quality (AHRQ)…. Read More ›
Author Insights: ICU Patients May Benefit From Alternative Sedative
Sedation is often required for patients in the intensive care unit (ICU) who are breathing with the assistance of a mechanical ventilator. But patients who are sedated for long periods can experience serious adverse effects, including delirium, posttraumatic stress disorder,… Read More ›
Author Insights: Stenting Not Appropriate for Treating Stable Coronary Artery Disease
Individuals with stable coronary artery disease, or stable angina, experience chest pain on exertion when narrowed or blocked arteries reduce the supply of oxygen-rich blood to the heart muscle. Current treatment calls for lifestyle changes and optimal medical therapy that… Read More ›
ACP to Congress: Fix Broken Politics to Preserve Needed Health Programs
The American College of Physicians (ACP) took aim today at the country’s “broken politics,” telling Congress that it should replace $1.2 trillion in across-the-board budget cuts beginning in 2013 with a new budget package that preserves essential health programs while… Read More ›
Attempt to Relieve Pressure After Brain Injury May Lead to Worse Outcomes
Disappointing results from an international clinical trial raise questions about the growing use of a surgical procedure that involves removing a portion of the skull to help relieve pressure on the brain after traumatic brain injury. The eagerly awaited results… Read More ›