Women exposed to diethylstilbestrol (DES) while still in the womb appear to face a lifetime increased risk for cancer and fertility problems, said researchers from the National Cancer Institute. Developed in 1938, DES was the first synthetic estrogen and was… Read More ›
While off-label use of atypical antipsychotics has skyrocketed in recent years, such treatment is beneficial for only a handful of conditions, an analysis published today in JAMA found. The US Food and Drug Administration has approved the use of atypical… Read More ›
A computer-based model was able to successfully predict the adverse effects of 2 drugs used to treat abnormal heart rhythm, suggesting the model may be a useful tool to screen potential drug candidates for the disorder, according to a study… Read More ›
Patients taking certain psychiatric drugs may experience serious neurological problems if they are given the antibacterial medication linezolid (sold under the brand name Zyvox) or methylene blue, a drug that is also used as a dye in some diagnostic procedures… Read More ›
An editorial appearing today in The Spine Journal sharply questions the objectivity of purportedly independent researchers participating in industry-funded studies of a product used in spinal fusion surgery. The editorial is part of a special issue of the journal that… Read More ›
San Diego—A class of medications called glitazones used to treat diabetes can result in leakage from blood vessels into the eye, a condition called macular edema that increases the likelihood of loss of vision, according to findings reported at the… Read More ›
The US Food and Drug Administration (FDA) has revised its recommendations on the use of drugs to treat anemia in patients with chronic kidney disease. Label changes announced today for red blood cell–boosting erythropoiesis-stimulating agents (ESAs) reflect evidence that the… Read More ›
Use of the anticonvulsant drug topiramate during pregnancy is associated with an increased risk of birth defects, such as cleft lip or cleft palate, according to a new warning from the US Food and Drug Administration. The warning is based… Read More ›
Off-label use of the asthma drug terbutaline to prevent preterm labor or for prolonged treatment of preterm labor is not efficacious and poses a risk of serious heart-related problems and death to the mother, according to a warning from the… Read More ›
Researchers have found that when bevacizumab (Avastin) is used in combination with chemotherapy or biological therapy, treatment-related mortality is greater than with chemotherapy alone. In this week’s JAMA, researchers from Stony Brook University Medical Center in Stony Brook, NY, detail… Read More ›
