Sooner is much better than later when giving clot-busting medication to treat patients with ischemic stroke, confirms research appearing today in JAMA. Intravenous tissue-type plasminogen activator (tPA), a medication that dissolves blood clots, is used to treat the hallmark of… Read More ›
Neurology
Researchers Try to Quantify NSAID Risks
A new analysis confirms many of the risks and benefits of commonly used painkillers but quantifies them in ways that should help clinicians and patients make more informed decisions about using the drugs to treat chronic pain. The meta-analysis, published… Read More ›
Alzheimer Disease Therapy Fails to Show Efficacy in Study
Patients with mild to moderate Alzheimer disease experienced no reduction in cognitive decline or preservation of functional abilities, according to findings of a phase 3 trial of intravenous immunoglobulin (IVIG, Gammagard). The announcement, by trial sponsor Baxter International, follows similar… Read More ›
More Evidence Exonerates Vaccines From Autism Link
A new analysis adds to existing evidence showing that recommended childhood immunizations do not increase the risk of autism spectrum disorder (ASD). Despite a 2004 review from the Institute of Medicine that concluded the measles, mumps, rubella, and thimerosal-containing vaccines… Read More ›
Clot Removal Appears No Better Than Standard Therapy for Ischemic Stroke
It seems logical that patients with more functional brain tissue after a severe ischemic stroke would reap greater benefits from removing the triggering clot than survivors with less viable tissue. But research presented today at the International Stroke Conference in… Read More ›
Author Insights: Signs of Brain Changes Linked to Mental Difficulties Found in Retired Football Players
Changes in the brain’s white matter may help explain why some former professional football players develop cognitive dysfunction and depression later in life, according to a study published in JAMA Neurology today. High-profile suicides of former National Football League (NFL) players… Read More ›
If a Renewed Prescription Involves Changes in Pill Color, Patients May Be Less Likely to Follow Through
Changes in pill color that patients often experience—typically when they switch from a brand-name drug to a generic version (or vice versa) or from one generic version to another—may make patients less likely to continue taking their medications as prescribed,… Read More ›
Physicians May Make a Difference in Concussion Surveillance
A small study of college ice hockey players in Canada in which physicians and other independent observers watched games from the stands and evaluated injured players indicates that college hockey players’ concussion rates there may have improved over the past… Read More ›
Rates of Epilepsy Remain Stable in the United States
Analysis of 2010 data suggests an estimated 1.0% of adults in the United States have active epilepsy. This percentage has remained stable since prevalence estimates were last calculated in 1994 using the same survey tool. The findings appear in today’s… Read More ›
Infectious Disease Experts Offer Updated Guidance on Fungal Meningitis Cases
San Diego—As the number of fungal meningitis cases linked to contaminated steroid injections rise, information about the outbreak and diagnosing and treating the infection continues to emerge. Since the initial report on September 21 to the US Centers for Disease… Read More ›